It had been reported that one lane was closed and with queuing traffic as a result of an incident involving five vehicles.
The southbound lane of the A34 was closed just north of Whitchurch at Whitway.
Emergency vehicles are in attendance, and many local residents witnessed three fire tenders heading out of town up Newbury Street.
It is believed the road has now been re-opened.
There have also been reports of an overturned vehicle on the A303 earlier today between the A34 at Bullington and Popham, also resulting in a closed lane.